Variable: From asymptomatic to symptomatic. Bone metastases can cause a wide range of symptoms that can impair the quality of life or shorten survival. Direct complications of bone involvement include severe pain, pathologic fractures, and epidural spinal cord compression hypercalcemia is also common related to bone mets-presented with increase serum calcium, mental status change, dehydration, etc.
Answered 10/6/2012
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From pain to...: Increased serum calcium causing constipation, drowsiness/somnolence, . To an unexplained fracture. Certain diseases (prostate, breast, lung) very commonly develop bony metastases, .
Answered 9/28/2016
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