A member asked:

What is msi analysis? when and why it should be done for a stage iii-c colon cancer patient before chemotherapy?

6 doctors weighed in across 2 answers

May help: The question requires a long answer but the abbreviated version is that certain markers such as msi have used to predict tumor behavior and tailor chemotherapy. If your doctor feel it may help you then it should be done.

Answered 12/10/2016

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Lynch Syndrome: "microsatellite instability" examines if there are defects in gene repair pathways causing cancer. Some of these can be hereditary, and may influence other treatments (such as hysterectomy for endometrial cancer risk in females). Recently, msi status has been used to predict benefit from chemo, although this has been more important for stage ii patients. Talk to your doctor for details!

Answered 11/9/2018

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