A member asked:

My mother has developed antiphospholipid syndrome. what is it exactly?

13 doctors weighed in across 2 answers

Autoimmune problem: With apa-s, the immune system produces antibodies against normal proteins in the body. Most importantly, blood clots can form in the legs and lungs, and there is a higher risk of strokes. As a gynecologist, I have concerns regarding a higher risk of miscarriages and stillbirths. Treatment centers on preventing a clot or treating one if it already exists.

Answered 5/1/2013

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Clot + blood test: Antiphospholipid syndrome is caused by a reaction between the immune system and a person's tissues which forms a blood clot in either an artery or vein. Diagnosis is made based on a clot and a positive blood test (anticardiolipin, lupus anticoagulant, b2-glycoprotein, rarely others). A "lacey" rash called livedo can occur. Clots cause miscarriages, strokes, heart attacks or deep vein thrombosis.

Answered 3/11/2016

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