A member asked:

My sister has biliary cirrhosis. should i be worried about it?

A doctor has provided 1 answer

Family risks for PBC: 90% of pbc patients are female. Age ranges 20-80, but typically patients are 40-60. The disease is world-wide, & affects asians, caucasians, jews, african. Family clustering is common in sisters, twins, daughters, mothers. While environmental factors can't be ignored, a strong immunogenetic background for pbc that runs in families is suggested. Early sxs: fatigue, itching before jaundice, RUQ pain.

Answered 6/23/2020

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