How will having biliary cirrhosis affect my long-term health?

Bad if untreated: An immuno-genetic disease, of which 90% are female, typically 40-60 years old. The disease affects asians, caucasians, jews, african. Family clustering is common. Early symptoms are fatigue, itching before jaundice, RUQ pain. Untreated pbc leads to progressive liver failure with its sequelae. Advanced age, liver/spleen enlargement, ascites, low albumin, fibrosis, cirrhosis predict worst prognosis.