A member asked:

Depakote, which i took (1, 000 mg/day) for 20 years, caused very high shbg levels. recently discontinued it. how long before shbg back to normal?

A doctor has provided 1 answer
Dr. Alvin Stein answered

Specializes in Pain Management

Is damage from depak: Depakote usually causes liver problems early in trealment and not 20 years after starting the drug. Your leukemia and the sprycel (dasatinib) may be the cause of the enzyme elevation. Sprycel (dasatinib) in involved in cyp450 in the liver and may be throwing your liver into trouble. , more likely that the depakote.

Answered 9/28/2016

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