How long is it supposed to it take for weight gained from taking prozac (fluoxetine) for 3 months to come off?

That depends on you.: The rate that you gained the weight does not effect the rate that you lose it. It will take a combination of physical activity and healthy food choices to start taking off the excess weight. Remember that it is 3, 500 calories per pound. To lose weight, your calories burned must exceed your calories consumed. Drink 8 - 8 ounces glasses of water per day. Good luck.