Why is leaky gut syndrome not accepted by medicine? it seems to make sense-insuf metab molec's enter blood trigger autoimmune complexes etc etc

We are science-based: There are many theories for many disorders, which shows that people are thinking and imagining the possibilities... and that is a great thing. Of course, it is the 21st century now, and no theory should be believed until it is shown to be true. That's the role of scientific research. So, no matter how good a theory sounds, it gets believed only when there is good research evidence to support it.

Failed basic tests: Forgive my frankness. Even the proponents of "leaky gut" accept tests that demonstrate increased absorption of certain sugars (sucrose, mannitol) as indicating the "disease". If this were a regular feature of rheumatoid arthritis, psoriasis, multiple sclerosis, or the other entities we're told are caused by "leaky gut", you'd see it regularly with them. You don't. For me, that settles it.

Good question: I a m a physician, and I have accepted the concept of leaky gut for 20 years. Medicine is an applied science and determining exact causality in the minds of some is necessary. So for example there are doctors hat acknowledge "gap junction" disruption, but still feel no link to autoimmune disease. As such do not accept paradigm.