What does doctors do if medications do not help mental illness?

Patience&Reevaluate: Sometimes, you have to wait longer for the expected result. Sometimes, the dosage has to be changed. Sometimes the specific medication has to be changed. Sometimes psychotherapy is indicated either with or without medication.

Medications not work: Depending on the type of illness, other modalities can include ECT (electro convulsive therapy), deep brain stimulation, acupuncture, meditation/yoga, etc.