A member asked:

Why is zoloft considered a "stronger" medication than lexapro (escitalopram) or celexa?

7 doctors weighed in across 2 answers
Dr. Robert Killian answered

Specializes in General Practice

Anti-Depressants: It is not a 'stronger' medication. It is of the same class and is a 'cousin' to Lexapro (escitalopram) and celexa. Most of us in medicine try to avoid such descriptive terms as 'stronger' 'better' or 'good' or 'bad' when discussing medications. One medication may be safer or 'more effective' than another in any given patient.. But, this question that you have asked before, has no correct answer.

Answered 5/12/2016

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Dr. Pamela Pappas answered

Specializes in Psychiatry

It's not, really: Zoloft is not really a "stronger" medication than Lexapro (escitalopram) or celexa. All 3 are selective serotonin reuptake inhibitors. They differ a little in the particular receptor sites they affect -- zoloft may block norepinephrine re-uptake a little more than Celexa and Lexapro (escitalopram) do, but not nearly as potently as paroxetine, duloxetine, and some older tricyclics.

Answered 1/24/2020

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