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A 21-year-old member asked:
Who develops interstitial cystitis?
2 doctor answers • 7 doctors weighed in

Dr. Phillip Porchanswered
41 years experience
Both men and women: It has a tendency to run in families which suggests a genetic factor. It is diagnosed more commonly in women.
6.2k viewsAnswered >2 years ago

Dr. Gurmukh Singhanswered
Pathology 50 years experience
30-40 yr old women: It is disease of unknown cause and affect women more than men and is more common around the age of 30-40 years. See this site for more info.
http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0001508/.
5.6k viewsReviewed Jan 04, 2021

Dr. Mitchell Schuster commented
Urogynecology 33 years experience
There seems to be a breakdown in the protective layer of the bladder called the GAG layer. There is a close correlation between I.C. and endometriosis. So, a family history of endometriosis or IC would place you at higher risk for development.
Sep 25, 2012
Similar questions
A 48-year-old member asked:
Interstitial cystitis -- what is it?
7 doctor answers • 14 doctors weighed in

Dr. Lester Thompsonanswered
Pathology 34 years experience
Bladder inflammation: The bladder has several layers, starting from the lining, through the muscle to the serosa (outer lining). The "interstitium" is between the muscle bundles. An inflammation of this area, results in "cystitis". It does not mean an infections, but it often is.
5.8k viewsAnswered >2 years ago
Last updated Jan 4, 2021
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