A member asked:

Is taking adderall (dextroamphetamine and racemic amphetamine) and rhodiola rosea a safe combination?

4 doctors weighed in across 2 answers
Dr. Rudolf Brutoco answered

Specializes in Child Psychiatry

Who knows??: We know a great deal about Adderall (dextroamphetamine and racemic amphetamine) - what it is, how it works, dosing considerations, how to use it safely & how not to use it. With rhodiola, not so much. It's a plant containing many chemicals; it varies a bit depending where/how grown. Studies are limited. Fda says no significant benefit. Biggest question is: why take it? Isn't there a scientifically validated med that addresses your issue?

Answered 9/13/2017

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Dr. Pamela Pappas answered

Specializes in Psychiatry

It's not clear: Adderall has a complex metabolic pathway, including the liver isoenzyme cyp2d6. Rhodiola rosea is a potent inhibitor of cyp3a4, a different enzyme system. There are no reports of specific interactions between Adderall & rhodiola, but rhodiola has been linked to increased heart rate in patients also taking Lexapro (escitalopram) (metabolized by cyp 3a4 & 2c19). I suggest caution because of incomplete data.

Answered 5/20/2018

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Safe limit for adderall (dextroamphetamine and racemic amphetamine)?

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