A member asked:

Can i take 5htp and gaba with zoloft (sertraline) and clonazepam? if so what is the safe amount of each? i am on 50mg of zoloft (sertraline).

4 doctors weighed in across 2 answers
Dr. Heidi Fowler answered

Specializes in Psychiatry

Not recommended: Both zoloft (sertraline) and 5thp will increase serotonin levels. The doses are often not well standardized in supplements - so you can't always be sure of the amount of active substance you are getting. Best to talk over with your prescribing psychiatrist. He or she can raise dose of zoloft (sertraline) if indicated.

Answered 2/8/2014

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Dr. Alan Ali answered

Specializes in Psychiatry

5HTP: I would not advise taking 5htp while on zoloft, (sertraline) due to additive effect on serotonin. Consult your doc.

Answered 8/31/2018

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