A member asked:

How long can prednisone be in your system?

A doctor has provided 1 answer
Dr. Thomas Namey answered

Specializes in Rheumatology

Depends!: Prednisone has a pre conversion half life off one hour. Prednisone is a converted into prednisolone, which also has "steroid" effects! its plasma half life as Prednisolone is 2-3 hours. So the total effect a duration of 18-36 hours. But once its out of your system it takes a while for your system to re-regulate itself as well.

Answered 6/19/2018

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