Would regular blood tests rule out kidney failure?

They help.: Two blood tests that pinpoint kidney funcion are the serum creatinine and the egfr (estimated glomerular filtration rate). Creatinine is a breakdown product of muscle cells; creatinine is eliminated by healthy kidneys. As kidneys work less well, the creatitine level rises in the blood. The egfr, on the other hand, will fall as kidney function declines.