What's the best way to end loose skin after rapid weight-loss?

Remove it surgically: Usually loose skin after significant weight loss lacks elasticity and fails to return to normal. Surgical treatment with tummy tuck, brachioplasty, or breast lift surgery works to remove excess skin. For minor excess skin problems consider treatment with retin a, (tretinoin) fraxel, laser, or ultherapy.

Surgery: First, congratulations on your weight loss! unfortunately the loose skin left behind can be a difficult problem. The good news is that plastic surgery has come a long way with surgical techniques available for correction. I would encourage you to seek out a board certified plastic surgeon to discuss your options.

Great for you: Plastic surgery / body contouring is the only solution.