I googled it: Long-term exposure 2 smoke-free nicotine by the use of nicotine-containing chewing gum is associated w' hyperinsulinemia &insulin resistance. Because Insulin resistance and irs r important risk factors, this finding is consistent with increased cardiovascular morbidity & mortality in long-term users of smokeless tobacco. http://circ.ahajournals.org/content/94/5/878.full.
Answered 5/5/2018
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