It depends.: It all depends on several factors such as kidney function, the body's ability to metabolize the medication, and the formulation of the medication, for example extended-release verses immediate release. As an example, Metoprolol Tartrate can be metabolized anywhere between 37.5 hours to 14 hours. When discontinuing therapy tapering is often employed to avoid spikes in blood pressure.
Answered 5/23/2015
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