Should i stayaway from vydican if i have weak kidneys?

Vicodin: Vicodin's components, hydrocodone & acetaminophen, are both metabolized by the liver; so no dose adjustment is usually necessary for kidney pts. However, if you have severe renal disease, be cautious with all meds. Vicodin is potentially more dangerous to the liver: the Acetaminophen portion (tylenol) can damage the liver if other tylenol-like meds are taken with it.

No: Vicodin, if used appropriately, is generally a very safe medication. The active ingredients are metabolized, or broken down, in the liver, not the kidney. Ibuprofen (the active ingredient in advil (ibuprofen) or motrin) and other "nsaid" drugs can have adverse effects on the kidney, and you should be careful with those.