Are some people more prone to getting traveler's diarrhea?

Yes: The people who go to places without water that's known to be clean and do not drink bottled water.

Yes: People who have gastro-esophageal reflux (gerd) and take certain medications which block acid production, such as Prilosec or nexium, (esomeprazole) are more likely to contract traveler's diarrhea (td). Also people who have underlying problems with immunity are more susceptible. If you are traveling to an area where td is common, drink bottled water, avoid ice, wash your hands, and eat cooked food served hot.