A member asked:

A spinal injury has me on fentanyl 100mcg & 10/500 hydro/acet .my pain tripled 28th&29th, took 15 ea day & now severe cramps. how concerned should be?

7 doctors weighed in across 2 answers
Dr. Vikram Patel answered

Specializes in Pain Management

Opiates: That is a very large dose of opiates in my opinion. Opiates do cause intestines to slow down which may lead to severe constipation. Did you take 15 tabs each day? Did you know that fentanyl has a black box warning to be used for cancer pain only? Opiates also cause "opiate induced hyperalgesia" meaning that the pain perception increases. You should think about 5 yrs from now.

Answered 12/30/2014

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GI tract : Narcotics can certainly slow your GI tract and cause constipation. If 15 is 5x your normal amount, your cramps are very likely related to this. That is a large amount of narcotic and i would see your physician for the very least to evaluate your pain intensity increasing to that level.

Answered 7/10/2015

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