Are some people more prone to getting primary pulmonary hypertension?

Yes: Pulmonary hypertension is a common consequence of heart disease like heart failure or mitral valve disease. Pulmonary hypertension that begins in the pulmonary artery is a more rare type of pulmonary HTN and it is more common in patients with hiv, autoimmune disease, congenital heart disease, certain liver disease, bloot clots, and use of methamphetmaine and certain weight loss medication.

It may be inherited: Up to 5% of patients with pulmonary arterial hypertension (pah) may have a genetic or heritable cause. Research studies have identified a genetic abnormality affecting bone morphogenetic protein receptor 2 (bmpr2) that appears to predispose a patient to pah. Fortunately, even if an individual inherits the abnormal gene, the likelihood of developing pah is only 1 in 5.