A member asked:

Can ana fluctuate in the winter vs. summer? had rash in winter that was possible early connective tissue disease per biopsy. have more pain in winter.

6 doctors weighed in across 2 answers

Possibly: Advise you see your rheumatologist and have titers checked. Connective tissue diseases can fluctuate in severity with the seasons, and many factors play a role.

Answered 1/21/2018

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Dr. Peter Kurzweil answered

Specializes in Internal Medicine

Perhaps, but sx more: There 100+ ct diseases (immunologic disorders (where one makes antibodies to own tissues); typical e.g. Are systemic lupus, scleroderma, rheumatoid arthritis, psoriasis; often can't categorize (mixed ct disease); rash or pain in winter may be cold air setting off small artery spasm (reynauds). ANA titer fluctuation not very important. Gloves, ear muffs, scarf, hand/feet warmers; rheumatologist.

Answered 1/1/2021

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