Which medicine for ulcer is most effective?

Depends on cause: Ulcers can occur at different areas in the gastrointestinal tract. A stomach ulcer may be due to irritation (most commonly medications such as ibuprofen) or may be due to a bacteria (called h. Pylori). Acid lowering medications such as prilosec, protonix, nexium, prevacid, or Aciphex (rabeprazole) may be helpful to allow the ulcer to heal. If it is due to h. Pylori, a specific antibiotic regimen is used.