What would the life expectancy of someone with sickle cell anemia be?

Shorter than average: It depends on the type and severity of the sickle cell anemia that you have and all complications related to the sickle cell anemia- i.e.Acute chest syndrome, strokes, avn, mi, etc. The life expectancy is unfortunately shorter than average population- in hb ss sickle cell anemia- on average it's around 40- 50 yrs of age. The more severe and more complications - the shorter the life span would be.