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A member asked:
For childbearing purpose, i'm genotype ac and my fiance is genotype as, can we continue with the relationship?. meanwhile, we both resides in uk?
A doctor has provided 1 answer
These are referring to the genotypes for sickle cell disease. If you have children, a quarter of the offspring will be expected to be AA, a quarter AC, a quarter AS and a quarter CS. AA is considered normal and CS is a form of sickle cell disease. AS is sickle cell trait and AC is hemoglobin C trait. Genetic counseling can be sought. Good luck!
Answered 9/12/2023
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