A member asked:

I've been taking doxycycline 100 mg as a prophylactic to std's. i've been taking it wrong for the last 3 days. i've been taking once a day instead of twice a day. should i ask my doctor to start me over from day 1?

2 doctors weighed in across 2 answers

No- generally this kind of variation taken for prophylaxis will not affect things much. However you can call your doc for their opinion

Answered 7/6/2023

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Dr. Hunter Handsfield answered

Specializes in Infectious Disease

Pre-exposure prophylaxis with doxycycline to prevent syphilis and chlamydia (Doxy-PrEP) is very effective for men who have sex with men at high risk (e.g. condomless sex). CDC soon will formally recommend it for MSM; many doctors already are prescribing it. The dose is 200 mg taken soon after sex and no later than 72 hr. It is not to be taken on an ongoing basis, just 1 dose after high risk sex.

Answered 7/7/2023

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