If i am starting tretinoin should i stop using benzoyl peroxide 5% cream that i have been using for a little over a year?

Although skin irritation can occur, some doctors sometimes allow benzoyl peroxide to be used with tretinoin to treat acne. Usually tretinoin is applied at night so that it does not cause a problem with any other topical products that you might use during the day.

Sometimes, both creams are used together, but it’d be good to clarify with your doctor whether the benzoyl peroxide (BP) should be continued. Keep in mind: both BP and tretinoin can make the skin more sensitive to sunlight - sunscreen can help. The two shouldn’t be applied to the same area at the same time – which is okay because BP’s usually applied during the day and tretinoin at night.