Been smoking crystal ice/meth for 2 years and i always test my product for cut and the product i get is pretty potent crystal but one problem i have is a chemical imbalance i never have gotten high from smoking crystal meth what could cause this?

In some cases, individuals who use methamphetamine may develop a tolerance to the drug, which means they need higher doses to achieve the desired effects. However, in other cases, individuals may not experience the expected effects of methamphetamine despite using potent crystal. This could be due to a variety of factors, including individual differences in brain chemistry and genetics.