While driving my husbands hands go numb. he also experiences numbness when applying pressure on his left leg. what could this be from and what to do.

Various etiologies: There are a number of different possible causes for this, from vitamin deficiency to nerve compression to pressure on his spinal cord. There are a few other things that could lead tho this, have him go get this worked up by his physician so that the cause is appropriately addressed.

2 conditions: These are unrelated complaints. The hand numbness may be carpal tunnel syndrome vs pinched cervical nerves. Numbness with the left leg is more likely a pinched nerve in the lumbar spine. Further evaluation with a physician is warranted if symptoms persist and/or are debilitating.