A member asked:

I have had 3 iron panels done over the last 3 years. my transferrin saturation is always high around 60%. my tibc is always in the low normal range. my ferritin is in the high normal range. i do not take supplements. is this an iron overload disease?

3 doctors weighed in across 2 answers

There are two tests to assess iron overload: 1.Genetic testing to test for proclivity to iron overload. 2. Liver biopsy to measure iron in the tissue. Visit this site for more info: https://www.mayoclinic.org/diseases-conditions/hemochromatosis/diagnosis-treatment/drc-20351448 Wish you good health!

Answered 12/27/2022

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Dr. Jay Park answered

The blood test results you described are not specific enough to suspect hereditary hemochromatosis (HH). Typical HH presents with high transferrin saturation and ferritin level, and abnormal liver function tests, e.g., elevated ALT, prothrombin time, etc. I would like to get another ferritin level and liver function test before considering MRI of liver or genetic testing.

Answered 12/31/2022

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