Difficult : BP change on talking to the comatose patient means his autonomic system is responding to some stimuli not necessarily speaking. I am not aware of study that has answered to this parameter for prognosis.
Answered 7/9/2019
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Maybe: Any physiologic response to an external stimulus can be a sign of responsiveness, which is better than unresponsiveness. So, if a coma patient has any change when stimulated (heart rate, blood pressure, movement), it can be a sign they sense the stimulus. We look for purposeful movement (pulling away from pain, grimacing) and eye opening as signs a patient may be starting to wake up.
Answered 7/8/2015
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