A member asked:

I dont understand how a syphilis test can be conclusive at 6 weeks with no need for further testing, if the window period can be up to 90 days? aren`t diagnoses missed this way?

A doctor has provided 1 answer
Dr. Hunter Handsfield answered

Specializes in Infectious Disease

There has been no precise research on time to positive syphilis blood tests. The screening tests (RPR, VDRL, EIA for IgG and/or IgM antibody) for sure are conclusive by 90 days, and probably positive over 95% of the time by 6 weeks. In my 40+ years in the STD business, I've never had a patient with negative results at 6 weeks who later had positive test results. If it happens, it is very rare.

Answered 10/22/2022

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