There has been no precise research on time to positive syphilis blood tests. The screening tests (RPR, VDRL, EIA for IgG and/or IgM antibody) for sure are conclusive by 90 days, and probably positive over 95% of the time by 6 weeks. In my 40+ years in the STD business, I've never had a patient with negative results at 6 weeks who later had positive test results. If it happens, it is very rare.
Answered 10/22/2022
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