Yes: There is no drug interaction between Loratadine (antihistamine) and Ibuprofen (nsaid). They can actually be taken simultaneously if needed.
Answered 6/27/2014
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Probably: Loraditine is an antihistamine that does not cause drowsiness. Ibuprofen pm also contains an antihistamine (to make you drowsy). So you would get more antihistamine than intended, but i would still not expect to experience significant side effects.
Answered 8/23/2014
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