Treatment of localy advanced breast cancer .large ulcerative mass of left breast.metastatic work up are free?

Combination likely: Surgery with wide margin and perhaps flap radiation depends on other factors.

Chemotherapy: If it is still localized consideration if chemotherapy first i shrink it brides using surgery and radiation may be needed. If it is more than a couple of cm then chemotherapy will be needed if it is felt that you could tolerate it. Radiation will help cleanup microscopic cells after surgical removal.

Combined therapy : It depends on the receptor status of the tumor. Is it estrogen receptor positive. Is it her 2 positive. ? Chemotherapy may help to shrink it to make surgery more effective. Usually a course of radiation would be necessary. If the ulcerating mass has an odor Flagyl cream/ointment can help reduce the odor