I take linzess my doctor just increased the dose to 290 i'm have been on that dose for four days i'm wondering if my severe headache and nausea are side effects of medication also have diarrhea please help. thank you?

Yes, they all can be side effects to linaclotide, specifically diarrhea that has to be reported to your doc timely. Other conditions cannot be ruled out, however timing points towards the drug causing diarrhea and related dehydration.

Although most reported side effects involve gastrointestinal issues, with diarrhea prominent, it would not be unusual to develop headaches and nausea secondary to the medication and resultant dehydration and potential electrolyte imbalance. Notify your doctor ASAP, as this likely is not a drug you can tolerate.