Can taking duphaston result in bad mood swings?

Short answer: Yes! This drug is a progesterone analog and can have significant effects on mood. Interestingly, it can both generate mood swings and stabilize them depending on the patient. I would need to know much more about you before I could give you meaningful advice about this. Your best course would be to discuss this with the physician writing the med for you.

Not likely. Duphaston contains dydrogesterone as an active ingredient. It is a synthetic form of the female hormone progesterone. If you are taking any other meds then go to Drugs.com and do interaction search as may affect the metabolism of other meds.