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A member asked:
Is it real that januvia (sitagliptin) 100mg made pancreas cells produce more insulin ( made beta cells more active )?
A doctor has provided 1 answer
Incretin: Januvia (sitagliptin) is an incretin which inhibits the breakdown of an enzyme called dpp-4. Dpp-4 breaks down glp-1. Glp-1 stimulates Insulin and inhibits glucagon (which raises glucose). Inhibition of glp-1 breakdown means it can stimulate more Insulin and inhibit more glucagon.
Answered 1/31/2017
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Related Questions
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I know Januvia (sitagliptin) max dose is 100mg daily. Are there cases where it can be taken in doses over 100mg? Its the only diabetic med that doesnt cause SE'S
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