Can long term use of famotodine cause problems?

Possibly : Best not to use famotidine long-term as it can potentially cause problems and periodic monitoring with labs would be recommended. I’d check with your doctor to see if there are any underlying causes that can can be addressed or if a taper is possible if you’ve been on long-term.

Talk to your Dr.: Famotidine is a histamine 2 blocker that decreases the amount of acid in the stomach. It is used to treat GERD, ulcers, esophageal erosions as well as Zollinger-Ellison syndrome and multiple endocrine neoplasia. Side effects can be severe and may increase the longer you take it, so many Doctors will keep the treatment regimen as short as needed to treat the current issue.