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A 37-year-old member asked:

Can you please tell me why it'sthat only males get hemophilia?

1 doctor answer2 doctors weighed in
Dr. Ahmad M Hadied
Orthopedic Surgery 50 years experience
Need to explain: This is because females have two x chromosomes while males have only one, so the defective gene is guaranteed to manifest in any male who carries it. Because females have two x chromosomes and haemophilia is rare, the chance of a female having two defective copies of the gene is very remote, so females are almost exclusively asymptomatic carriers of the disorder.
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Last updated Dec 10, 2013

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