A member asked:

Can pcos present with high estrogen/very high fsh, but mostly normal periods (occasional missed cycle)?

A doctor has provided 1 answer
Dr. Stuart Hickerson answered

Specializes in Family Medicine

Polycystic ovaries: PCOS is associated with high androgen levels derived from ovary or adrenal cortex. Serum LH is elevated but FSH is normal. Ovarian production of androgens due to ovarian insulin resistance. High circulating androgens/insulin resistance impairs normal ovulatory cycle.

Answered 10/21/2019

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