A member asked:

Is rexulti processed through the liver or kidneys?

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Dr. Susan Rhoads answered

Specializes in Family Medicine

Liver;: Rexulti (brexpiprazole) is mainly metabolized by the Cytochrome P450 enzyme system in the liver, and its metabolites are then excreted by the kidneys. See https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927015/ and also: See https://www.merckmanuals.com/home/drugs/administration-and-kinetics-of-drugs/drug-metabolism

Answered 2/6/2019

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