A member asked:

Can i take half of my dose of zoloft in the morning and half at night?

5 doctors weighed in across 2 answers
Dr. Hamsa Jayaraj answered

Specializes in Internal Medicine

Ask psychiatrist: The recommendation is once daily, but if taken twice need to take it at noon.

Answered 7/28/2018

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I wouldn't bother: Zoloft is not like some meds that get out of your system relatively quickly. The time it takes for 1/2 to leave your system is 26 hrs. After you take it once a day for several days it begins to have a steady level in your tissues on that once a day dosing. Spreading the dose out will not change the effect or side effects over time, but would increase the chance you will forget to take it.

Answered 7/30/2018

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