Can too much or too little spinal fluid cause headaches?

Yes...: Most people have a constant volume of spinal fluid (about 150 ml in adults). People make enough spinal fluid every day to replace the volume about 4 times. The "old" fluid is absorbed as "new" is made. If the relative volume of spinal fluid increases (which would cause an increase in intracranial pressure), then the patient might have a headache. Hope this helps!