My sister (17y) is experiencing acne since puberty. various doctors gave acne treatment creams. no difference so far. what's the best treatment and remedy you advice? what about laser acne treatments? so far there's no significant improvement.

Lots of options: After working with one's primary care doctor and a dermatologist, a patient will have gone through several types of medications and can fine a combination of drugs that work for her. Options include gels or creams such as: benzoyl peroxide, clindamycin, erythromycin, retinoids, dapsone, etc...; and oral drugs such as: erythromycin, tetracycline, retinoids, combination hormones (OCPs), etc...