A member asked:

Can you take amitriptyline 10 mg tablets with duromine 15 mg tablets?

3 doctors weighed in across 3 answers
Dr. Heidi Fowler answered

Specializes in Psychiatry

Possible side effect: There is some potential for use of amitriptyline with phentermine to cause side effects such as ^’ed blood pressure, rapid or irregular heart rate, fever or headache. Sometimes dose adjustments are needed. This does not necessarily mean that the drugs can’t be used together. Info is from Drugs.Com drug interaction checker.

Answered 10/9/2018

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Dr. answered

Potentially trouble: The two drugs interact in a way that can sometimes cause serious effects. The combination is best avoided if possible. f you need to take both, then it must be done in conjunction with your family doctor who can monitor for drug interaction effects closely.

Answered 12/12/2017

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Dr. answered

Serotonin syndrome: With agitation/sweats/nausea etc is a rare side effect that can occur when these medicines interact. Most experts in NZ would still use the 2 in low dose with precaution but worth discussion with your GP re the pros and cons. May not be a trivial decision to stop the amitriptyline but I dont know the reason you're on it

Answered 12/12/2017

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