I took 1mg of lorazepam this evening, and about two hours later, my 100mg dose of nucynta. safe? feel ok but nervous i took too close together.

Drugs.Com: Drug Interaction Checker indicated" Using narcotic pain or cough medications together with other medications that also cause central nervous system depression can lead to serious side effects including respiratory distress, coma, and even death.." It doesn't sound like you took particularly high doses - but I would not drive, handle dangerous machinery, etc- until this wears off. Would NOT >

Avoid combination : Very risky to combine a sedative and an opioid. This can depress your breathing and this is how accidental deaths happen. Take your pain medication earlier and use something like Melatonin for sleep

Well : you should follow your own physician's recommendation. In general it's unlikely that taking these two medications together would have any significant side effects. This is generally buys