Which antidepressants, antianxiety, antipsychotics are the most effective and safest?

Depends: This is a complicated question that your own psychiatrist (who knows you and your situation) is best able to answer. All these medicines have fairly predictable effects, but different people have different needs & tolerances -- which in turn affect selection of the most helpful medicines for a given person. Safety also depends on other medicines taken, and other existing clinical conditions.