Taking 20mg losec 2x daily. have started taking cider vinegar and honey 2/3 times. any problem having these together?

Unlikely : Honey and cider vinegar not well studied in terms of therapies from a conventional medical perspective. However the cider vinegar is acidic and so may counteract the effects of the losec

No: But do not expect any medical benefit from vinegar or honey. The only rational reason to swallow either of these is because you like the taste. Otherwise you are just another sucker wasting money on silly, make-believe remedies.