Any docs familiar with tumefactive multiple sclerosis? ever seen a persistently enhancing lesion? 4cm lesion 5yrs enhancement. rr symptoms. 5 ocb.

Generic response: "Tumefactive" lesions are not uncommon in MS, and may be associated with even very potent medications. From your description, would presume your diagnosis is correct for R/R MS, but the lesion in question may be a co-morbidity, such as a vascular malformation, a brain glioma, or even a nidus of infection, such as abscess. Need to see your neurologist and go through careful and thorough testing.